Faculty Biography

Nehal Parikh, DO, MS

Back

Education:

DO (Doctor of Osteopathic Medicine): New York College of Osteopathic Medicine of New York Institute of Technology, Old Westbury, NY

Residency (Pediatrics): Winthrop University Hospital of State University of New York at Stony Brook, Mineola, NY

Fellowship (Neonatal-Perinatal Medicine): Thomas Jefferson University Hospital of Jefferson Medical College, Philadelphia, PA

MS (Master of Science in Clinical Research): University of Texas Medical School at Houston, Houston, TX

Clinical and Research Interests:

• Early detection and prevention of perinatal and neonatal brain injury in extremely premature infants
• Application of advanced MRI technologies to predict long-term outcomes
• Ethical dilemmas and decision-making in the care of extremely premature infants
• Therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy
• Evidence-based medicine

Publications (selected):

• Katsetos, C.D., Del Valle, L., Geddes, J.F., Assimakopoulou, M., Legido, A., Boyd, J.C., Balin, B., Parikh, N.A., Maraziotis, T., de Chadarevian, J.P., Varakis, J.N., Matsas, R., Spano, A., Frankfurter, A., Herman, M.M., and Khalili, K. Aberrant Localization of the Neuronal Class III Beta-tubulin in Astrocytomas. Arch Pathol Lab Med. 125(5):613-24, 2001.
• Parikh, N.A., Katsetos, C.D., Ashraf, Q.M., Haider, S.H., Legido, A., Delivoria-Papadopoulos, M., and Mishra, O.P. Hypoxia-Induced Caspase-3 Activation and DNA Fragmentation in Cortical Neurons of Newborn Piglets: Role of Nitric Oxide. Neurochem Res. 28(9):1351-1357, 2003. 
• Parikh, N.A., Locke, R.L., Paul, D.A., Chidekel, A., Leef, K., Emberger, J., and Stefano, J.L. The Effect of Inhaled Corticosteroids on Markers of Pulmonary Inflammation and Lung Maturation in Preterm Infants with Evolving Chronic Lung Disease. J Am Osteopath Assoc. 104(3):114-120, 2004.
• Sorrentino, D.F., Fritz, K.I., Haider, S.H., Parikh, N.A., Delivoria –Papadopoulos, M., and Mishra, O.P. Nitric Oxide Mediated Modification of the Glycine Binding Site of the NMDA Receptor during Hypoxia in the Cerebral Cortex of the Newborn Piglet. Neurochem Res. 29(2):455-459, 2004.
• Lasky, R.E., Luck, M.L., Parikh, N.A., and Laughlin, N.K. The Effects of Early Lead Exposure on the Brains of Adult Rhesus Monkeys: A Volumetric MRI Study. Toxicol Sci. 85(2):963-975, 2005.
• Gupta, R.K., Hasan, K.M., Trivedi, R., Kanabar, B., Pradhan, M., Das, V., Parikh, N.A., and Narayana, P.A. Diffusion Tensor Imaging of the Developing Human Cerebrum. J Neurosci Res. 81(2):172-178, 2005.
• Katsetos, C.D., Parikh, N.A., Fritz, K.I., Legido, A., Delivoria-Papadopoulos, M., and Mishra, O.P. Effect of 7-Nitroindazole Sodium on the Cellular Distribution of Neuronal Nitric Oxide Synthase in the Cerebral Cortex of Hypoxic Newborn Piglets. Neurochem Res. 31(7):899-906, 2006.
• Parikh, N.A., Lasky, R.E., Kennedy, K.A., Moya, F.R., Hochhauser, L., Romo, S., and, Tyson, J.E. Postnatal Dexamethasone Therapy and Cerebral Tissue Volumes in Extremely Low Birth Weight Infants. Pediatrics. 119(2):265-272, 2007.
• Tyson, J.E., Parikh, N.A., Langer, J., Green, C., Higgins, R., Intensive Care for Exreme Prematurity - Moving Byond Gestational Age. N Engl J Med. 2008;358(16):1672-81.
• Mietzsch, U., Parikh, N.A., Willaims, A.L., Shankaran, S., and Lasky, R.E. Effects of Hypoxic-Ischemic Encepathopathy and Whole-Body Hypothermia on Neonatal Auditory Function: A Pilot Study. Am J of Perinatol. 2008. In press.
• Developed a mortality and neurosensory impairment Web based risk assessment tool for 22 to 25 week gestation preemies
• Parikh, N.A. "The Brain". Editors: Bradt, PJ and Herbert, D. High Risk. A Handbook for the Aftercare of Premature Infants. Savage Design, Houston, TX: 12-13, 2004.
• *Parikh, N.A., Ashraf, Q.M., Legido, A., Chadarevian, J.P., Katsetos, C.D. Expression of Neuronal Nitric Oxide Synthase during Hypoxia in the Cerebellum of Newborn Piglets. Pediatr Res. 2001;49(4);442A.
• *Parikh, N.A., Fritz, K.I., Zu, A., Mishra, O.P., Delivoria-Papadopoulos, M. Effect of Neuronal Nitric Oxide Synthase (nNOS) Inhibition on DNA Fragmentation in Neuronal Nuclei During Hypoxia in Newborn Piglets. Pediatr Res. 2001;49(4)45A.
• ªParikh, N.A.,Locke R.G., Chidekel, A., Leef, K.H., Emberger, J., Paul D.A., Stefano, J.L. Effect of Inhaled Corticosteroids on Inflammatory Cytokines in Preterm Infants with Evolving Chronic Lung Disease. Pediatr Res. 2002;51(4);356A.
• ªParikh, N.A., Katsetos, C.D., Fritz, K.I., Legido, A., Mishra, O.P. Neuronal Nitric Oxide Synthase Expression Following Hypoxia in the Cerebral Cortex of Newborm Piglets. Pediatr Res. 2002;51(4);461A.
• Parikh, N.A., Katsetos, C.D., Fritz, K.I., Legido, A., Mishra, O.P. Effect of Neuronal Nitric Oxide Synthase (nNOS) Inhibition on Caspase-3 Expression During Hypoxia in the Cerebral Cortex of Newborm Piglets. Pediatr Res. 2003;53(4);63A.
• €Parikh, N.A., Lasky, R.E., Tyson, J.E., Moya, F.R., Kennedy, K.A. Effects of Postnatal Dexamethasone on Cerebral Tissue Volumes in Extremely Low Birth Weight Infants. PAS 2005:57:1505A.
• §Parikh, N.A., Tyson, J.E., and the NICHD Neoantal Research Network. Viability, Treatment, and Outcome at 18-22 Months for Extremely Premature Infants. E-PAS 2006:59:5531.175.
• ψParikh, N.A., Lasky, R.E., Garza, C., Bonfante-Mejia, E., Shankaran, S., Tyson, J.E. Relationship of MRI Cerebral Tissue Volume to Neurosensory Outcomes and Whole-Body Hypothermia Therapy for Hypoxic-Ischemic Encephalopathy. E-PAS 2008:59:5365.7.
• Presented at the Pediatric Academic Society - Soceity for Pediatric Research (PAS-SPR) international meeting in 2001* (Baltimore, MD), in 2002ª (Baltimore, MD), in 2005€ (Washington, DC), in 2006§ (San Francisco, CA) and in 2008ψ (Honolulu, HI).

Location & Contact

6431 Fannin Street
MSB 3.020
Houston, Texas 77030
713-500-5757 (Voice)

Faculty Biography

• Nehal Parikh, DO, MS
  Assistant Professor
• Department of Pediatrics
  Division of Neonatal-Perinatal Medicine
• University of Texas-Houston Medical School
  6431 Fannin Street, MSB 3.236B
  Houston, Texas 77030
• phone: (713) 500-6470
  fax: (713) 500-5794
  e-mail: Nehal.A.Parikh@ uth.tmc.edu
• Executive Assistant:
  Kim Self (713) 500-5727