Department of Pediatrics
Department of Pediatrics
The Department of Pediatrics

Faculty Biography

The Department of Pediatrics at the University of Texas Medical School at Houston is dedicated to improving the health and welfare of all infants, children, and adolescents.


Amir M. Khan, MD

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Education:

M.B., B.S., Aga Khan University, Karachi, Pakistan

Residency, University of Texas-Houston Medical School, Houston, TX

Fellowship, University of Texas-Houston Medical School, Houston, TX

Clinical and Research Interests:

  1. Lung inflammation in meconium aspiration syndrome
  2. Genetic interplay in alveolar type II epithelial cell function
  3. Gene-environment interactions and development of childhood asthma
  4. GERD and chronic lung disease
  5. Ventilatory strategies in neonatal lung diseases
  6. Use of ECMO in neonatal and pediatric respiratory failure

Publications (selected):

  • Castro SM, Guerrero-Plata A, Suarez-Real G, Adegboyega PA, Colasurdo GN, Khan AM, Garofalo RP, Casola A. Antioxidant Treatment Ameliorates Respiratory Syncytial Virus-induced Disease and Lung Inflammation. Am J Respir Crit Care Med. 74(12):1361-9. 2006
  • Colasurdo GN, Fullmer JJ, Elidemir O, Atkins CL, Khan AM, Stark JM. Respiratory Syncytial virus infection in a murine model of cystic fibrosis. J Med Virol. 78(5):651-8, 2006.
  • Jon CK, Stark JM, Khan AM, Alcorn JL, Atkins BS, Xue H, Schecter MG, Larsen GL, Colasurdo GN. Genetic susceptibility to RSV Infection in Inbred Mouse Pups: Important role of SP-A. Proc Am Thoracic Soc 2006; 3: A411.
  • Lawson JK, Colasurdo GN, Atkins CL, Khan AM, Schecter MG, Stark JM. Exposure of Newborn Mice to LPS Protects from Allergen (Ovalbumin)-Induced airway Hyperresponsiveness and Airway Remodeling Independent of Th1/Th2 Pathways. Proc Am Thoracic Soc 2006; 3: A153.
  • Stark JM, Jon CK, Khan AM, Atkins BS, Stark MA, Xue H, Larsen GL, Colasurdo GN. Effect of Genetic Background and Age on Airway Responsiveness Following RSV Infection in Inbred Mouse Pups. Proc Am Thoracic Soc 2006; 3:412.
  • Schecter MG, Morandi M, Holian A, Khan AM, Atkins CL, Jon CK, Stark JM, Colasurdo GN. Functional an Cellular Response to Lipopolysaccharide and Particulate Matter (PM-1648 and PM-Hou) in Developing Mice. Proc Am Thoracic Soc 2006; 3: A 553.
  • Shah BS, Khan AM, Atkins CL, Schecter MG, Jon CK, Colasurdo GN and Stark JM. Age-Dependent differences in Disease Severity and Inflammatory Responses to RSV Infection in Young and Aged Mice. Submitted 2006 American Thoracic Society International Conference, San Diego, CA Proc Am Thoracic Soc 2006; 3:781.
  • Fullmer JJ, Khan AM, Elidemir O, Chiappetta C, Stark JM, Colasurdo GN. Role of Cysteinyl Leukotrienes in Airway Inflammation and Responsiveness Following RSV Infection in BALB/c Mice, Pediatr Allergy Immunol. 16(7):593-601, 2005.
  • Khan AM and Lally KP. Role of extracorporeal membrane oxygenation in the management of infants with congenital diaphragmatic hernia. Semin Perinatol. 29(2):118-22, 2005
  • Stark JM, Khan AM, Chiappetta C, Xue H, Patel T, Colasurdo GN. Immune and Functional Role of Nitric Oxide in a Mouse Model of RSV Infection. Infect Dis. 191:387-95, 2005.
  • Khan AM, Atkins CL, Xue H, Holian A, Stark JM, Colasurdo GN. SP-A Depletion Enhances Particulate Matter (PM)-Induced Changes in Airway Responsiveness and Inflammation in Mice PAS 57: 2384, 2005
  • Khan F, Khan AM, Khattak AZ, Moya FR. Thromboxane and Prostacycline Plasma Levels and the Response to Inhaled Nitric Oxide Therapy in Neonates with Hypoxemic Respiratory Failure PAS 57: 2539, 2005
  • Weisoly DL, Khan AM, Elidemir O, and Smith KC. Congenital Tuberculosis and Extracorporeal Membrane Oxygenation. Pediatr Pulmonol. 37(5):470-3. 2004
  • Miller J, Colasurdo GN, Khan AM, Jajoo C, Patel TJ, Fan LL, Elidemir O. Immunocytochemical detection of milk proteins in tracheal aspirates of ventilated infants: A pilot study. Pediatr Pulmonol 34(5):369-74 2002.
  • Khan AM, Elidemir O, Epstein CE, Lally KP, Xue H, Blackburn M, Larsen GL, Colasurdo GN, Meconium aspiration produces airway hyperresponsiveness and eosinophilic inflammation in a murine model. Am J Physiol Lung Cell Mol Physiol 283: L785-L790, 2002.
  • Cochran JR, Khan AM, Elidemir O, Xue H, Cua B, Larsen GL, Colasurdo GN Influence of Lipopolysaccharide Exposure on Airway Function and Allergic Responses in Developing Mice. Pediatr Pulmonol 34(4):267-77 2002.
  • Khan AM, Lally KP, Elidemir O, Colasurdo GN. Meconium Enhances the Release of Nitric Oxide in Human Airway Epithelial Cells. Biol Neonate. 81(2):99-104 2002.
  • Khan AM, Lally KP, Larsen GN, Colasurdo GN: Enhanced Release of Thromboxane A2 after Exposure to Meconium in Human Airway Epithelial Cells. Pediatr Pulmonol 33(2):111-6, 2002.
  • Gill W, Nevile H, Khan AM, Cox CS, Lally KP. Delayed Institution of ECMO is Associated with Increased Mortality and Prolonged Hospital Stay. J Pediatr Surg 37(1): 7-10, 2002.
  • Khan AM, Shabarek FM, Kutchback JW, Lally KP: Effects of dexamethasone on meconium aspiration syndrome in newborn piglets Pediatr Res 46: 179-183, 1999.
  • Khan AM, Shabarek F, Zwischenberger J, Warner B, Goretesky M, Myers T, Cheu H, Jaksic T, Lally K: Utility of daily head ultrasonography for infants on extracorporeal membrane oxygenation. J Pediatr Surg. 1998; 33(8): 1229-1232.

 

Faculty Biography

Dr. Amir M. Khan
  • Amir M. Khan, MD
    Associate Professor
  • Department of Pediatrics
    Division of Neonatal-Perinatal Medicine and Pulmonary, Critical Care & Allergy-Immunology Medicine
  • Medical Director, Respiratory Care, Children's Memorial Hermann Hospital
  • Medical Director of Transport Team, Children's Memorial Hermann Hospital
  • University of Texas-Houston Medical School
    6431 Fannin Street, MSB 3.230A
    Houston, Texas 77030
  • phone: (713) 500-5650
    fax: (713) 500-0588
    e-mail: Amir.M.Khan@ uth.tmc.edu
  • Staff Assistant:
  • Roxanne Lopez (713) 500-5733
Click for my PubMed publications